Schematic illustration of... - Yale Image Finder

Related Figures

Figure 3 Graphs visualizing correlation analyses ...

Figure 4 Co-regulatory networks of Arabidopsis WR...

Figure 2 Graph demonstrating correlation between ...

Fig. 1 Correlations of the three methodologies ...

Figure 4 Correlations of virological parameters a...

Figure 6 Great variation in DNA accessibility amo...

Figure 1 Correlation between CI measured in the p...

Figure 4 Comparison of RQ-TRAP and TRAP-ELISA res...

Figure 3 Correlation between the similarity matri...

Figure 2 Behavioral Findings.The graphs display t...

Figure 4: Schematic illustration of graph analysis applied to multi channel recordings of brain activity (fMRI, EEG or MEG). The first step (panel A) consists of computing a measure of correlation between all possible pairs of channels of recorded brain activity. The correlations can be represented in a correlation diagram (panel B, strength of correlation indicated with black white scale). Next a threshold is applied, and all correlations above the threshold are considered to be edges connecting vertices (channels). Thus, the correlation matrix is converted to a unweighted graph (panel C). From this graph various measures such as the clustering coefficient C and the path length L can be computed. For comparisons, random networks can be generated by shuffling the cells of the original correlation matrix of panel B. This shuffling preserves the symmetry of the matrix, and the mean strength of the correlations (panel D). From the random matrices graphs are constructed, and graph measures are computed as before. The mean values of the graph measures for the ensemble of random networks are determined. Finally, The ratio of the graph measures of the original network and the mean values of the graph measures of the random networks can be determined (panel F).

Image Text (High Precision): i

Other Images from "Graph theoretical analysis of complex networks in the brain":

Figure 1 Representation of a network as a graph. ...

Figure 3 Scale-free graphs are characterized by a...

Figure 2 Three basic network types in the model o...

Figure 4 Schematic illustration of graph analysis...

[Full Text] [PDF]

Abstract

Since the discovery of small-world and scale-free networks the study of complex systems from a network perspective has taken an enormous flight. In recent years many important properties of complex networks have been delineated. In particular, significant progress has been made in understanding the relationship between the structural properties of networks and the nature of dynamics taking place on these networks. For instance, the 'synchronizability' of complex networks of coupled oscillators can be determined by graph spectral analysis. These developments in the theory of complex networks have inspired new applications in the field of neuroscience. Graph analysis has been used in the study of models of neural networks, anatomical connectivity, and functional connectivity based upon fMRI, EEG and MEG. These studies suggest that the human brain can be modelled as a complex network, and may have a small-world structure both at the level of anatomical as well as functional connectivity. This small-world structure is hypothesized to reflect an optimal situation associated with rapid synchronization and information transfer, minimal wiring costs, as well as a balance between local processing and global integration. The topological structure of functional networks is probably restrained by genetic and anatomical factors, but can be modified during tasks. There is also increasing evidence that various types of brain disease such as Alzheimer's disease, schizophrenia, brain tumours and epilepsy may be associated with deviations of the functional network topology from the optimal small-world pattern.